Split Hand/Foot Malformation with Long Bone Deficiency: A Report of Two Female Siblings
Published: June 1, 2021 | DOI: https://doi.org/10.7860/JCDR/2021/48104.15060
Mohammed Ali Al-Shehab
, Ahmed Saleh Hudna
, Fahd Naji Thawaba
,Farouk Abdulrahman Al-Qadasi
1. Senior Specialist, Department of Paediatrics, University of Science and Technology Hospital, Sana’a, Yemen.
2. Assistant Professor, Department of Paediatrics, University of Science and Technology, Sana’a, Yemen.
3. Consultant, Department of Radiology, University of Science and Technology Hospital, Sana’a, Yemen.
4. Postgraduate, Department of Statistics, International Organisation of Migration, Sana’a, Yemen
Correspondence
Dr. Mohammed Ali Al-Shehab,
Al-Steen Street, Sana’a, Yemen.
E-mail: dr.m.alshehab@gmail.com
Spilt Hand/Foot Malformation with Long bone Deficiency (SHFMLD) is a rare heterogeneous group of limb malformations characterised by absence/hypoplasia and/or median cleft of hands and/or feet associated with long bone abnormalities, most frequently tibia. This case report described two sisters with congenital limb defects born to healthy consanguineous parents. The six-year-old girl did not had both radii and the left fibula. There was a cleft in the left hand and the right foot. She had one digit in her right upper limb, but did not have the left foot. The four-year-old girl had four short limbs, bilateral tibial aplasia with single digit in all limbs. Both parents were normal, and no other similar cases were reported in the family. According to the authors’ best knowledge, these two cases are the first published cases in Yemen with SHFMLD, but they need a genetic study to determine their genetic profile.
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